Mangaluru: KMC Hospital Attavar successfully managed and treated a rare, life-threatening autoimmune condition, showcasing advanced multidisciplinary medical care and clinical expertise.

The patient, who underwent nearly three months of intensive treatment, was diagnosed with lupus presenting as rapidly progressive glomerulonephritis (RPGN) along with life-threatening recurrent lung bleeding, making the case highly complex.

Complex condition with multi-organ involvement

The illness involved multiple organ systems, requiring prolonged hospitalisation and continuous monitoring. The patient’s condition posed significant challenges due to the severity of autoimmune activity combined with critical complications.

Severe infection adds to treatment challenge

During the course of treatment, the patient developed mucormycosis of the lung, a serious fungal infection requiring aggressive management.

Doctors administered four weeks of intravenous Amphotericin B, while carefully balancing immunosuppressive therapy needed to control the autoimmune disease.

Advanced multidisciplinary treatment approach

The patient underwent a series of advanced treatments, including:

  • Multiple sessions of plasma exchange
  • Rituximab therapy
  • Intravenous immunoglobulin (IVIG)
  • Carefully monitored corticosteroid therapy

The case was managed by the Department of Rheumatology, in collaboration with the Nephrology team and Infection Services, ensuring a coordinated and comprehensive approach.

Successful recovery and discharge

Following intensive treatment, the patient showed steady recovery, including:

  • Stabilisation of kidney function
  • Resolution of lung complications
  • Effective control of infection

The patient was subsequently discharged in a stable condition, marking a successful outcome in a highly critical case.

Centre of excellence in autoimmune care

KMC Hospital Attavar continues to be recognised for its expertise in managing complex autoimmune and inflammatory diseases, particularly those involving multiple organ systems.

This case highlights the importance of timely diagnosis, multidisciplinary coordination, and advanced treatment protocols in achieving positive outcomes in rare and life-threatening conditions.